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免疫疗法或可有效避免糖尿病并发症

首页 » 研究 » 糖尿病 2014-12-01 转化医学网 赞(2)
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免疫计划疗法和传统的疗法在治疗糖尿病上到底有什么差异?病人一般进行诊断后会严密观察,但同时也会进行系统性的免疫问题的检查来预防可能性的一些疾病,比如糖尿病足、青光眼、视网膜病变和肾病变等。只要患者机体的免疫问题不被攻击,那么其糖尿病就不会完全被控制,因为这些患者都存在一定的免疫缺陷,而且更易于感染。

 免疫计划疗法和传统的疗法在治疗糖尿病上到底有什么差异?病人一般进行诊断后会严密观察,但同时也会进行系统性的免疫问题检查来预防可能性的一些疾病,比如糖尿病足、青光眼、视网膜病变和肾病变等。只要患者机体的免疫问题不被攻克,那么其糖尿病就不会完全得到控制,因为这些患者都存在一定的免疫缺陷,而且更易于感染。
  研究者Sigfrido Miracle Lopez表示,对于1型糖尿病来讲,患者机体的胰腺组织会被破坏或者胰岛素产生细胞会被破坏,但是相同状况的病人或许会存在其它的自身免疫疾病,也同时影响着其它的器官功能。这种称之为自身免疫性多内分泌腺综合征,这种情况下机体会攻击胰腺和甲状腺,而且同时会引发甲状腺功能减退、风湿性关节炎等疾病。
  目前研究人员正在寻找不仅只有一种疾病的患者,还在寻找患多种疾病的患者;当患者进行治疗时,医生们会集中进行患者糖类的管理疗法,因为糖类会引发糖尿病患者患其它疾病,而且常常会被患者忽视;因此从免疫学角度来看,攻克糖尿病的关键就是去分析患者机体整体的状况,而不单单是患者机体的一种状况。
  在研究者所在的研究中心,患者会进行一种全方位的疾病状况评估,检测患者机体的自身免疫问题及未来有可能引发的并发症,如果患者未来有患其它疾病的风险,研究人员就会施以疗法来预防患者其它疾病的发生。当患者接受特殊的治疗糖尿病的疗法,注射胰岛素或口服降糖药物,患者都将会接受免疫球蛋白类的治疗来控制机体的疾病症状和自身免疫疾病。
  最后研究者表示,目前研究中心不仅要观察患者的疾病、而且还要严密观察患者本人及其它影响患者病情的所有因素,对这些因素的有效控制和管理对于抑制糖尿病患者机体疾病并发症的发生非常关键。(转化医学网360zhyx.com)
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As long as the immune problem is not attacked diabetes cannot be fully controlled, because these patients have immunodeficiency (decreased defenses) and are more prone to infections, said Sigfrido Miracle Lopez, chief of endocrinology at the Advanced Immunology Center in the Angeles Hospital of Mexico City.
"In the case of Type I diabetes, patients suffer destruction of the pancreas or of the insulin producing cells, but this same patient may have other autoimmune diseases that can affect other organs. This is called autoimmune polyglandular syndrome, a situation in which the body attacks the pancreas, thyroid and may develop hypothyroidism, adrenal insufficiency, or rheumatoid arthritis," he explained.
The Advanced Immunology Center seeks to serve not only patients who have one ailment, but a group of diseases, that can be diagnosed or not, and who are at risk of developing other conditions that can be treated holistically.
When the patient attends to the endocrinologist, the physician only focuses on the management of sugar, which causes that other diseases that will have repercussions in the future are not being diagnosed in time and get discarded. Therefore, the purpose of attacking diabetes from an immunological point of view, is to analyze the entire body and not just the one condition, the endocrinologist highlighted.
In the Center, the patient will be evaluated in a comprehensive manner, to detect the autoimmune problem that caused, him or her, diabetes or further complications. If the patient has further repercussions, treatment will be given to prevent the development of other diseases......

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