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NHGRI奖2830万美元促进基因调控秘密的揭示

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美国国家人类基因组研究所(NHGRI)今天宣布其为奖励解读打开和关闭基因的潜在机制申请了2830万美元的拨款。

  美国国家人类基因组研究所(NHGRI)今天宣布其为奖励解读打开和关闭基因的潜在机制申请了2830万美元的拨款。

  该笔款项分别拨给了五个科研机构和大学。其中320万美元拨给了斯隆凯特林癌症中心,用来鼓励其在小鼠炎症机制的免疫系统活动研究;拨给了杜克大学590万美元,鼓励其在人类肺上皮细胞应对糖皮质激素类消炎药物时的细胞反应机制方面的研究;马萨诸塞大学医学院获得610万美元来研究树突状细胞在免疫系统中的作用;斯坦福大学获得710万美元研究皮肤细胞角化细胞的成熟和发展;加州大学洛杉矶分校获得600万美元研究巨噬细胞对细菌病原体的影响。

  NHGRI基因组科学部门项目分析总监Mike Pazin说:“该项政府拨款旨在鼓励了解、开发细胞网络中基因和基因组开关组合的新途径。细胞网络中基因和基因组开关组合的相关知识对于人类健康和疾病的基因多样化研究至关重要。”

  (转化医学网360zhyx.com)

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  转化医学网推荐的新闻阅读:
  The National Human Genome Research Institute today announced it has awarded $28.3 million in grants to decipher the underlying mechanisms that turn genes on and off.
  The grants have been awarded to Memorial Sloan Kettering Cancer Center, which received $3.2 million to study mechanisms of immune system activity during inflammation in mice; Duke University, which got $5.9 million to characterize how human lung epithelial cells respond to anti-inflammatory drugs called glucocorticoids; the University of Massachusetts Medical School, which was granted $6.1 million for the study of dendritic cells in the immune system; Stanford University, which received $7.1 million to study the maturation and development of keratinocyte skin cells; and the University of California, Los Angeles, which was awarded $6 million to study macrophage response to bacterial pathogens.
  "The GGR program aims to develop new ways for understanding how the genes and switches in the genome fit together as networks. Such knowledge is important for defining the role of genomic differences in human health and disease," said Mike Pazin, a program director in the Functional Analysis Program in NHGRI's Division of Genome Sciences.
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